Van Aken  lab

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Peer-reviewed Journal articles

 

Tran HC, Schmitt V, Lama S, Wang C, Launay-Avon A, Bernfur K, Sultan K, Khan K, Brunaud V, Liehrmann A, Castandet B, Levander F, Rasmusson AG, Mireau H, Delannoy E, Van Aken O§. (2023) An mTRAN-mRNA interaction mediates mitochondrial translation initiation in plants. Science. 381(6661): eadg0995 (IF 56.9, 1 citation). §corresponding author

 

Schmitt V, Van Aken O§. (2023) Mitophagy: From the dark into the spotlight. Mol Plant. 16(10): 1487-1489 (IF 27). §corresponding author

 

Darwish E, Ghosh R, Bentzer J, Tsardakas Renhuldt N, Proux-Wera E, Kamal N, Spannagl M, Hause B, Sirijovski N, Van Aken O§. (2023) The dynamics of touch-responsive gene expression in cereals. Plant J (116(1): 282-302) (IF 7.1, 2 citations) §corresponding author

 

Kacprzak SM, Van Aken O§. (2023) FRIENDLY is required for efficient dark-induced mitophagy and controlled senescence in Arabidopsis. Free Rad Biol Med 204:1-7 (IF 8.01, 3 citations) §corresponding author

 

Bhattacharya A, Majtorp L, Birgersson S, Wiemann M, Sreenivas K, Verbrugghe P, Van Aken O, Van Niel EWJ, Stålbrand H. (2022) Cross-Feeding and Enzymatic Catabolism for Mannan-Oligosaccharide Utilization by the Butyrate-Producing Gut Bacterium Roseburia hominis A2-183. Microorganisms 10(12):2496. (IF 4.9)

 

Khan K, Van Aken O§. (2022) The colonization of land was a likely driving force for the evolution of mitochondrial retrograde signalling in plants. J Exp Bot 73(21):7182-7197. doi: 10.1093/jxb/erac351. PMID: 36055768 (IF 7.3) §corresponding author

 

Ruberti C, Feitosa-Araujo E, Xu Z, Wagner S, Grenzi M, Darwish E, Lichtenauer S, Fuchs P, Parmagnani AS, Balcerowicz D, Schoenaers S, de la Torre C, Mekkaoui K, Nunes-Nesi A, Wirtz M, Vissenberg K, Van Aken O, Hause B, Costa A, Schwarzländer M. (2022) MCU proteins dominate in vivo mitochondrial Ca2+ uptake in Arabidopsis roots. Plant Cell 34(11):4428-4452. doi: 10.1093/plcell/koac242. (IF 11.28)

 

Darwish E, Ghosh R, Ontiveros-Cisneros A, Tran HC, Petersson M, De Milde L, Broda M, Goossens A, Van Moerkercke A, Khan K, Van Aken O§. (2022) Touch signaling and thigmomorphogenesis are regulated by complementary CAMTA3- and JA-dependent pathways. Sci Adv. 8(20):eabm2091. doi: 10.1126/sciadv.abm2091. §corresponding author (IF 14.14)

 

Ontiveros-Cisneros A, Moss O, Van Moerkercke A, Van Aken O§. (2022) Evaluation of Antibiotic-Based Selection Methods for Camelina sativa Stable Transformants. Cells 11(7):1068. §corresponding author (IF 6.6).

 

Kacprzak SM, Van Aken O§. (2022) Carbon starvation, senescence and specific mitochondrial stresses, but not nitrogen starvation and general stresses, are major triggers for mitophagy in Arabidopsis. Autophagy (Accepted with minor revisions) §corresponding author (IF 16.0)

 

Li Y, Belt K, Alqahtani SF, Saha S, Fenske R, Van Aken O, Whelan J, Millar AH, Murcha MW, Huang S. (2022) The mitochondrial LYR protein, SDHAF1 is required for succinate dehydrogenase activity in Arabidopsis. Plant J. in press doi: 10.1111/tpj.15684. (IF 6.4)

 

Møller IM, Rasmusson AG, Van Aken O. (2021) Plant mitochondria - past, present and future. Plant J. 108(4):912-959. (IF 6.4)

 

Broda M, Khan K, O’Leary B, Pružinská A, Lee CP, Millar AH, Van Aken O§ (2021) Increased expression of ANAC017 primes Arabidopsis for accelerated senescence. Plant Physiol 186(4):2205-2221 (IF 8.3)

 

Van Aken O§. (2021) Mitochondrial redox systems as central hubs in plant metabolism and signalling. Plant Physiol (epub 24 Feb 2021) §corresponding author (IF 8.3)

 

Verbrugghe P, Van Aken O, Hållenius F, Nilsson A (2021) Development of a real-time quantitative PCR method for detection and quantification of Prevotella copri. BMC Microbiol. 21(1):23 (IF 3.2)

 

Tran HC, Van Aken O§. (2020) Mitochondrial unfolded protein-related responses across kingdoms: similar problems, different regulators. Mitochondrion 53: 166-177 §corresponding author (IF 4.0)

 

Pfannschmidt T, Terry MJ, Van Aken O, Quiros PM. (2020) Retrograde signals from endosymbiotic organelles: a common control principle in eukaryotic cells. Phil Trans Royal Soc B. 375(1801):20190396 (IF 6.1)

 

Adamowicz-Skrzypkowska A, Kwasniak-Owczarek M, Van Aken O, Kazmierczak U, Janska H. (2020) Joint restriction of two terminal mitochondrial oxidases, complex IV and AOX, represses chloroplast transcription in Arabidopsis. Phil Trans Royal Soc B. 375(1801):20190409 (IF 6.1)

 

Kacprzak MS, Dahlqvist A, Van Aken O§. (2020) The transcription factor ANAC017 is a key regulator of mitochondrial proteotoxic stress responses in plants. Phil Trans Royal Soc B. 375(1801):20190411 (IF 6.1) §corresponding author

 

Van Moerkercke A, Duncan O, Zander M, Šimura J, Broda M, Vanden Bossche R, Lewsey MG, Lama S, Singh KB, Ljung K, Ecker JR, Goossens A, Millar AH, Van Aken O§. (2019) A MYC2/MYC3/MYC4-dependent transcription factor network regulates water spray-responsive gene expression and jasmonate levels. Proc Natl Acad Sci U S A. 116: 23345-23356. (IF 12.8) §corresponding author

 

Wagner S, Steinbeck J, Fuchs P, Lichtenauer S, Elsässer M, Schippers JHM, Nietzel T, Ruberti C, Van Aken O, Meyer AJ, Van Dongen JT, Schmidt RR, Schwarzländer M. (2019) Multiparametric real-time sensing of cytosolic physiology links hypoxia responses to mitochondrial electron transport. New Phytol. 224:1668-1684 (IF 7.3, 6 citations)

 

Lama S, Broda M, Abbas Z, Vaneechoutte D, Belt K, Säll T, Vandepoele K, Van Aken O§. (2019) Neo-functionalisation of mitochondrial proteins and incorporation into signalling networks in plants. Mol Biol Evol 36: 974-989 (IF14.7). §corresponding author

 

Ryan MH, Kaur P, Nazeri NK, Clode P, Keeble-Gagnere G, Doolette AL, Smernik RJ, Van Aken O, Nicol D, Millar AH, Appels R. (2019) Globular structures in roots accumulate phosphorus to extremely high concentrations following phosphorus addition. Plant Cell Environ 42: 1987-2002 (IF 6.2)

 

Belt K, Van Aken O, Murcha M, Millar AH, Huang S. (2018) An assembly factor promotes assembly of flavinated SDH1 into the succinate dehydrogenase complex. Plant Physiol 177, 1439-1452. (IF 6.3, 5 citations)

 

Broda M, Millar AH, Van Aken O§. (2018) Mitophagy: a mechanism for plant growth and survival. Trends Plant Sci 23: 434-450 §corresponding author (impact factor 12.9, 14 citations)

 

Wagner S, Van Aken O, Elsässer M, Schwarzländer M. (2018) Mitochondrial energy signaling and its role in the oxygen stress response of plants. Plant Physiol 176: 1156-1170. (IF 6.3, 26 citations)

 

Van Aken O§, Pogson BJ. (2017) Convergence of mitochondrial and chloroplastic ANAC017/PAP-dependent retrograde signalling pathways and suppression of programmed cell death. Cell Death & Diff 24(6): 955-960 §corresponding author (IF 8.2, 25 citations)

 

Jonas Blomme, Van Aken O, Jelle Van Leene, Teddy Jégu, Riet De Rycke, Twiggy Van Daele, Liesbeth De Milde, Geert De Jaeger, Moussa Benhamed, Harvey Millar, Dirk Inzé & Nathalie Gonzalez.  (2017) Arabidopsis SWIB5 is a mitochondrial DNA-binding protein involved in homologous recombination. Plant Cell, 29(5): 1137-1156 (IF 8.5, 6 citations)

 

Belt K, Huang S, Thatcher L, Casarotto H, Singh K, Van Aken O, Millar AH. (2017) Salicylic acid-dependent plant stress signalling via mitochondrial succinate dehydrogenase. Plant Physiol 173(4):2029-2040. (IF 6.3, 37 citations)

 

Xinhua Zhang, Aneta Ivanova, Klaas Vandepoele, Jordan Radomiljac, Jan Van de Velde, Patrick Willems, Oliver Berkowitz, Sophia Ng, Veronique Storme, Van Aken O, Owen Duncan, Botao Zhang, Kai Xun Chan, Dries Vaneechoutte, Barry Pogson, Frank Van Breusegem, James Whelan, and Inge De Clercq. (2017) Identification of the MYB29 transcription factor as a negative regulator of ALTERNATIVE OXIDASE 1a in Arabidopsis. Plant Physiol 173(3):1824-1843 (IF 6.3, 19 citations).

 

Van Aken O§, Ford E, Lister R, Huang S, Millar AH. (2016) Retrograde signalling during heritable mitochondrial dysfunction is partially mediated by ANAC017 and improves plant performance. Plant J 88: 542-558 §corresponding author (IF 5.7, 23 citations)

 

Van Aken O§, De Clercq I, Ivanova A, Law SR, Van Breusegem F, Millar AH, Whelan J (2016). Mitochondrial and chloroplast stress responses are modulated in distinct touch and chemical inhibition phases in Arabidopsis. Plant Physiol 171(3):2150-65 §corresponding author (impact factor 6.3, 33 citations)

 

Huang S, Van Aken O, Schwarzländer M, Belt K, Millar AH. (2016) The roles of mitochondrial reactive oxygen species in plant signalling and stress response. Plant Physiol 171(3):1551-9. (impact factor 7.4, 153 citations)

 

Wang Y, Lyu W, Berkowitz O, Radomiljac JD, Law SR, Murcha MW, Carrie C, Teixeira PF, Kmiec B, Duncan O, Van Aken O, Narsai R, Glaser E, Huang S, Roessner U, Millar AH, Whelan J. (2016) Inactivation of mitochondrial complex I induces the expression of a twin cysteine protein that targets and affects cytosolic, chloroplastidic and mitochondrial function. Mol Plant (S1674-2052). (IF 7.1, 14 citations)

 

Wagner, S, Behera S, De Bortoli S, Logan D, Fuchs P, Carraretto L, Teardo E, Cendron L., Nietzel T, Fussl M, Fricker M, Van Aken O, Finkemeier I, Meyer A, Szabo I, Costa A, Schwarzländer M. (2015) The EF-Hand Ca2+ binding protein MICU choreographs mitochondrial Ca2+ dynamics in Arabidopsis. Plant Cell 27: 3190-3212 (Impact factor 8.5, 62 citations)

 

Van Aken O§, Van Breusegem F. (2015) Licensed to kill: mitochondria, chloroplasts and cell death. Trends Plant Sci 20: 754-766 (impact factor 12.9, 75 citations) §corresponding author

 

Zhang B*, Van Aken O*§, Thatcher L, De Clercq I, Duncan O, Law SR, Murcha MW, van der Merwe M, Seifi HS, Carrie C, Cazzonelli C, Radomiljac J, Hofte M, Singh K, Van Breusegem F, Whelan J§. (2014) The mitochondrial outer membrane AAA ATPase AtOM66 affects cell death and pathogen resistance in Arabidopsis thaliana. Plant Journal 80: 709-727 (impact factor 5.3, 44 citations). *These authors contributed equally; § corresponding author

 

Wang Y, Law SR, Ivanova A, Van Aken O, Narsai R, Uggalla V, van der Merwe M, Duncan O, Whelan J and Murcha MW. (2014). The mitochondrial protein import component, TRANSLOCASE OF THE INNER MEMBRANE17-1, plays a role in defining the timing of germination in Arabidopsis. Plant Physiol (impact factor 6.3, 9 citations)

 

Ivanova A, Law SR, Narsai R, Duncan O, Lee JH, Zhang B, Van Aken O, Radomiljac JD, van der Merwe M, Yi K, Whelan J. (2014) A Functional Antagonistic Relationship between Auxin and Mitochondrial Retrograde Signaling Regulates Alternative Oxidase1a Expression in Arabidopsis. Plant Physiol 165:1233-1254 (impact factor 6.3, 43 citations)

 

Ng S, De Clercq I, Van Aken O, Law S, Willems P, Ivanova A, Giraud E, Van Breusegem F, Whelan J. (2014) Anterograde and Retrograde Regulation of Nuclear Genes Encoding Mitochondrial Proteins During Growth, Development and Stress. Mol Plant 7: 1075-1093 (impact factor 7.1, 96 citations)

 

De Clercq I, Vermeirssen V, Van Aken O, Vandepoele K, Murcha MW, Law SR, Inzé D, Ng S, Ivanova A, Rombaut D, van de Cotte B, Japsers P, Van de Peer Y, Kangasjärvi J, Whelan J, Van Breusegem F. (2013) The Membrane-Bound NAC Transcription Factor ANAC013 Functions in Mitochondrial Retrograde Regulation of the Oxidative Stress Response in Arabidopsis. Plant Cell 25: 3472-90 (impact factor 9.6, 183 citations)

 

Ng S, Ivanova A, Duncan O, Law SR, Van Aken O, De Clercq I, Wang Y, Carrie C, Xu L, Kmiec B, Walker H, Van Breusegem F, Whelan J, Giraud E. (2013) A Membrane-Bound NAC Transcription Factor, ANAC017, Mediates Mitochondrial Retrograde Signaling in Arabidopsis. Plant Cell 25:3450-71. (impact factor 9.6, 172 citations)

 

Van Aken O, Zhang B, Law S, Narsai R, Whelan J. (2013) AtWRKY40 and AtWRKY63 modulate the expression of stress-responsive nuclear genes encoding mitochondrial and chloroplast proteins. Plant Physiol. 162:254-271. (impact factor 7.4, 114 citations)

 

Van Aken O, Whelan J. (2012) Comparison of transcriptional changes to chloroplast and mitochondrial perturbations reveals common and specific responses in Arabidopsis. Front Plant Sci. 3:281 (impact factor 4.5, 57 citations)

 

Zhang B, Carrie C, Ivanova A, Narsai R, Murcha MW, Duncan O, Wang Y, Law SR, Albrecht V, Pogson B, Giraud E, Van Aken O, Whelan J. (2012). LETM proteins play a role in the accumulation of mitochondrially encoded proteins in Arabidopsis thaliana and AtLETM2 displays parent of origin effects. J Biol Chem. 287:41757-73. (impact factor 4.6, 35 citations)

 

Giraud E, Van Aken O, Uggalla V, Whelan J. (2011) REDOX regulation of mitochondrial function in plants. Plant, Cell & Environment 35: 271-80. (impact factor 6.2, 25 citations)

 

Giraud E, Ng S, Duncan O, Carrie C, Low J, Lee CP, Van Aken O, Millar H, Murcha M, Whelan J. (2010) TCP transcription factors link the regulation of genes encoding mitochondrial proteins with the circadian clock in Arabidopsis thaliana. Plant Cell 22: 3921-34. (impact factor 9.6, 138 citations)

 

Tognetti V*, Van Aken O*, Morreel K., Vandenbroucke K, De Clercq I, van de Cotte B, Prinsen E, Chiwocha S, Fenske R, Stubbs K, Boerjan W, Inze D, Van Breusegem F (2010). Perturbation of indole-3-butyric acid homeostasis by UDP-glucosyltransferase UGT74E2 modulates Arabidopsis architecture and water stress tolerance. Plant Cell. 22: 2660-79. *these authors contributed equally. (impact factor 8.5, 290 citations)

 

Van Aken O§, Whelan J, Van Breusegem F. (2010) Prohibitins: mitochondrial partners in development and stress response. Trends in Plant Science. 15: 275-82. §: corresponding author (impact factor 12.9, 64 citations)

 

Skirycz A, De Bodt S, Obata T, De Clercq I, Claeys H, De Rycke R, Andriankaja M, Van Aken O, Van Breusegem F, Fernie AR, Inzé D (2009) Developmental stage specificity and the role of mitochondrial metabolism in the response of Arabidopsis leaves to prolonged mild osmotic stress. Plant Physiol 152: 226-44. (impact factor 7.4, 231 citations)

 

Van Aken O, Zhang B, Carrie C, Uggalla V, Paynter E, Giraud E, Whelan E (2009) Defining the mitochondrial stress response. Mol Plant 2: 1310-24. (impact factor 7.1, 144 citations)

 

Giraud E*, Van Aken O*, Ho LHM and Whelan J. T (2009) The transcription factor ABI4 is a regulator of mitochondrial retrograde expression of alternative oxidase 1a. Plant Physiol. 150: 1286-96. *these authors contributed equally (impact factor 6.3, 206 citations)

 

Van Aken O§, Giraud E, Clifton R and Whelan J. (2009) The alternative oxidase: a target and regulator of stress responses. Physiol Plant. 137:354-61. §: corresponding author (impact factor 3.7, 203 citations)

 

Ho LHM, Giraud E, Uggalla V, Lister R, Glen A, Thirkettle-Watts D, Van Aken O and Whelan J. (2008) Identification of regulatory pathways controlling gene expression of stress responsive mitochondrial proteins in Arabidopsis. Plant Physiol. 147: 1858-1873 (impact factor 6.3, 119 citations)

 

Pellny TK, Van Aken O, Dutilleul C, Wolff T, Groten K, Bor M, De Paepe R, Reyss A, Van Breusegem F, Noctor G, Foyer CH. (2008) Mitochondrial respiratory pathways modulate nitrate sensing and nitrogen-dependent regulation of plant architecture in Nicotiana sylvestris. Plant J. 54: 976-992 (impact factor 5.7, 64 citations)

 

Van Aken O, Pecenková T, van de Cotte B, De Rycke R, Eeckhout D, Fromm H, De Jaeger G, Witters E, Beemster GT, Inzé D, Van Breusegem F. (2007) Mitochondrial type-I prohibitins of Arabidopsis thaliana are required for supporting proficient meristem development. Plant J. 52: 850-864 (impact factor 5.7, 113 citations)

 

 

Scholarly Books

 

Van Aken O and Rasmusson AG. (2022) Methods in Molecular Biology: Plant Mitochondria. 2363

 

 

Scholarly Book Chapters (peer reviewed)

 

Tran HC, Van Aken O. (2022) Purification of Leaf Mitochondria from Arabidopsis thaliana Using Percoll Density Gradients. Methods Mol Biol. 2363:1-12. Edited by Olivier Van Aken and Allan G Rasmusson (in press).

 

Annual Plant Reviews: Plant Mitochondria. “Plant mitochondria and cell death”.

Van Aken O. Edited by David C Logan ISBN: 978-1-118-90659-0, December 2017

 

Methods in Molecular Biology: Plant Programmed Cell Death “Studying retrograde signalling in plants”. Broda M, Van Aken O*. Edited by Laura De Gara & Vittoria Locato (p73-85). *Corresponding author

 

Plant Physiology and Development, 7th Edition. “Mitochondria-to-nuclear ‘retrograde’ signalling in plants” Web-essay. Van Aken O. Edited by Taiz, Zeiger, Møller and Murphy